Alternative preservation strategies are increasingly important as traditional preservatives face stricter regulations and consumer’s demand grows for clean ingredients. Multifunctional ingredients including caprylyl glycol, 1,2-hexanediol, and ethylhexylglycerin are critical tools for cosmetic formulators pursuing alternative preservation strategies.
Korea Cosmetic Regulation Framework – https://www.mfds.go.kr/eng/brd/m_28/down.do?brd_id=eng0006&seq=71481&data_tp=A&file_seq=1
United States Food & Drug Administration – https://www.fda.gov/cosmetics/cosmetics-laws-regulations/prohibited-restricted-ingredients-cosmetics
European cosmetic ingredient database (Cosing) – https://data.europa.eu/data/datasets/cosmetic-ingredient-database-list-of-preservatives-allowed-in-cosmetic-products?locale=en
China National Medical Products Administration – http://english.nmpa.gov.cn/cosmetics.html
Japan Ministry of Health and Welfare Notification – https://www.mhlw.go.jp/english/dl/cosmetics.pdf
When choosing between multifunctional ingredients such as caprylyl glycol, 1,2-hexanediol, and ethylhexylglycerin, formulators should take many factors into consideration including pH, water activity, solubility, and compatibility. These ingredients often need to be used in combination with other ingredients in order to provide broad spectrum anti-microbial performance.