{"id":6135,"date":"2008-11-10T16:51:42","date_gmt":"2008-11-10T16:51:42","guid":{"rendered":"http:\/\/sacheminc.com\/?p=6135"},"modified":"2013-08-27T22:17:30","modified_gmt":"2013-08-27T22:17:30","slug":"sachem-article-helps-chromatographers-understand-displacement-chromatography","status":"publish","type":"post","link":"https:\/\/www.sacheminc.com\/ko\/sachem-article-helps-chromatographers-understand-displacement-chromatography\/","title":{"rendered":"SACHEM Article Helps Chromatographers Understand Displacement Chromatography"},"content":{"rendered":"<p>Article in\u00a0<em>Chromatography Techniques<\/em>\u00a0tells why displacement Chromatography is an indispensable tool for the purification of biomolecules.<\/p>\n<p><strong>Austin, TX<\/strong>\u00a0&#8211;\u00a0<strong>November 10, 2008<\/strong>\u00a0&#8211; Dr. Charles Little, Principal Chemist at SACHEM, Inc., has authored an\u00a0<a title=\"Displacement Chromatography 101\" href=\"\/?page_id=3719\" target=\"_blank\">article<\/a>\u00a0in\u00a0<em>Chromatography Techniques\u00a0<\/em>journal<em>\u00a0<\/em>titled, &#8220;Displacement Chromatography Comes of Age.&#8221;\u00a0 The article highlights the benefits of\u00a0displacement chromatography\u00a0over elution chromatography for the purification of biomolecules.\u00a0 The article includes a history of elution mode chromatography and displacement chromatography, a process description of the three stages of displacement separation, and a discussion of the benefits and advantages of displacement chromatography.<\/p>\n<p>&#8220;Displacement chromatography is very useful in\u00a0<a title=\"Protein Purification\" href=\"\/?page_id=3703\" target=\"_blank\">protein purification<\/a>,\u00a0<a title=\"Oligonucleotide Purification\" href=\"\/?page_id=3699\" target=\"_blank\">oligonucleotide purification<\/a>,\u00a0quality assurance, biocomparability, and process control.\u00a0 As chromatographers we want to understand available purification tools and how to pick the best one for our specific applications,&#8221; states Dr. Little. Displacement chromatography is fast becoming an indispensible tool for purification of biomolecules of commercial interest, including oligonucleotides.\u00a0 It enables a higher degree of purification in fewer steps than most commonly practiced techniques.\u00a0 Best of all, it requires no specialized equipment or materials other than a high-purity, efficient displacer, and can be practiced on the bench or in the plant.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Article in\u00a0Chromatography Techniques\u00a0tells why displacement Chromatography is an indispensable tool for the purification of biomolecules. Austin, TX\u00a0&#8211;\u00a0November 10, 2008\u00a0&#8211; Dr. Charles Little, Principal Chemist at SACHEM, Inc., has authored an\u00a0article\u00a0in\u00a0Chromatography Techniques\u00a0journal\u00a0titled, &#8220;Displacement Chromatography Comes of Age.&#8221;\u00a0 The article highlights the benefits of\u00a0displacement chromatography\u00a0over elution chromatography for the purification of biomolecules.\u00a0 The article includes a history &hellip;<\/p>\n","protected":false},"author":43,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"wds_primary_category":0,"footnotes":""},"categories":[9,1],"tags":[],"class_list":["post-6135","post","type-post","status-publish","format-standard","hentry","category-news","category-uncategorized","no-thumb"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/posts\/6135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/comments?post=6135"}],"version-history":[{"count":0,"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/posts\/6135\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/media?parent=6135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/categories?post=6135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sacheminc.com\/ko\/wp-json\/wp\/v2\/tags?post=6135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}