TETRABUTYLAMMONIUM FLUORIDE (TBAF)
SACHEM’s Tetrabutylammonium Fluoride 98% (TBAF) represents the purity, precision and power of a non-aqueous source of fluoride for organic reaction systems. SACHEM offers TBAF in a trihydrate form, which is readily soluble in the common medium THF.

Key Attributes and Features of TBAF
  • Availability in trihydrate form (TBAF * 3H2O) for minimum water content for applications requiring "anhydrous" fluoride
  • Easily soluble in organic solvents as opposed to other sources of fluoride (such as KF/crown); TBAF's solubility will allow design of appropriate reaction systems
  • "Anhydrous" source of fluoride; the lack of significant amounts of water leaves the fluoride "naked", or accessible, and much more reactive
  • Unique base and non-nucleophilic properties of TBAF can be used in basecatalyzed cyclizations and conjugate additions
  • Si-F bonding, one of the strongest single bonds known; TBAF in dry THF can desilylate TBDMS (tert-butyldimethylsilyl)-protected alcohols
TBAF Product Availability
Our global network of facilities and seamless logistical support can supply TBAF anywhere in the world, consistently, reliably and at various quantities.    
  • Commercial scale manufacturing capability in bulk quantities
  • Packaging of TBAF trihydrate 25 kg and 50 kg fiber drums
Experience the precision and power of unique base and non-nucleophilic properties in your organic reaction with SACHEM’s Tetrabutylammonium Fluoride 98% (TBAF).

Available Products

Tetrabutylammonium Fluoride Trihydrate

98%, (TBAF 98% Trihydrate)
M/SDS  |  SDS [13 KB]  |  Datasheet [40 KB]