At SACHEM, we have harnessed over 50 years of expertise in providing high purity, precision chemical solutions and combined it with innovative displacement chromatography technology to create a portfolio of enabling displacers called Expell™, Propell™, and Isolis™ for use in protein and oligonucleotide purification and impurity isolation.

Creating Solutions Where Chemistry and Biology Meet

At SACHEM, we have harnessed over 50 years of expertise in providing high purity, precision chemical solutions and combined it with innovative displacement chromatography technology to create a portfolio of enabling displacers called Expell™, Propell™,  and Isolis™ for use in protein and oligonucleotide purification and impurity isolation. 

Expell™: Cation, anion, HIC and reverse phase displacers for use in Protein Purification via displacement chromatography

Propell™: Anion and reverse phase displacers for use in oligonucleotide purification via displacement chromatography

Isolis™: Cation, anion and reverse phase displacers for use in impurity isolation via displacement chromatography

These displacers are designed and manufactured with high purity and precision.  They operate on the molecular level in order to solve your most challenging processing issues and support the most demanding applications.   

New SACHEM eLearning Course on Displacement Chromatography

To learn more about displacement chromatography, see example results, view a quick animation or take a 20 minute interactive e-learning course.

From discovery to commercialization, SACHEM’s displacers and displacement chromatography lower costs, shorten cycle time and improve product purity in a wide range of applications.

SACHEM provides a consistent, reliable supply of high purity displacers in quantities that support applications from the laboratory to plant production.