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TETRABUTYLAMMONIUM FLUORIDE (TBAF) |
SACHEM’s Tetrabutylammonium Fluoride 98% (TBAF) represents the purity, precision and power of a non-aqueous source of fluoride for organic reaction systems. SACHEM offers TBAF in a trihydrate form, which is readily soluble in the common medium THF.
Synthetic Utility for TBAF
Key Attributes and Features of TBAF
- Availability in trihydrate form (TBAF * 3H2O) for minimum water content for applications requiring "anhydrous" fluoride
- Easily soluble in organic solvents as opposed to other sources of fluoride (such as KF/crown); TBAF's solubility will allow design of appropriate reaction systems
- "Anhydrous" source of fluoride; the lack of significant amounts of water leaves the fluoride "naked", or accessible, and much more reactive
- Unique base and non-nucleophilic properties of TBAF can be used in basecatalyzed cyclizations and conjugate additions
- Si-F bonding, one of the strongest single bonds known; TBAF in dry THF can desilylate TBDMS (tert-butyldimethylsilyl)-protected alcohols
TBAF Product Availability
Our global network of facilities and seamless logistical support can supply TBAF anywhere in the world, consistently, reliably and at various quantities.
- Commercial scale manufacturing capability in bulk quantities
- Packaging of TBAF trihydrate 25 kg and 50 kg fiber drums
Experience the precision and power of unique base and non-nucleophilic properties in your organic reaction with SACHEM’s Tetrabutylammonium Fluoride 98% (TBAF).
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