1. Zhang, W.-N.; He, H.-B.; Feng, Y.-Q.; Da, S.-L., Separation of phosphatidylcholine and phosphatidylethanolamine by using high-performance displacement chromatography. Journal of Chromatography, A 2004, 1036, (2), 145-154.
2. Xiang, R.; Horvath, C.; Wilkins, J. A., Elution-Modified Displacement Chromatography Coupled with Electrospray Ionization-MS: On-Line Detection of Trace Peptides at Low-Femtomole Level in Peptide Digests. Analytical Chemistry 2003, 75, (8), 1819-1827.
3. Tugcu, N.; Deshmukh, R. R.; Sanghvi, Y. S.; Cramer, S. M., Displacement chromatography of anti-sense oligonucleotide and proteins using saccharin as a non-toxic displacer. Reactive & Functional Polymers 2003, 54, (1-3), 37-47.
4. Schmidt, B.; Wandrey, C.; Freitag, R., Investigation of particle-based and monolithic columns for cation exchange protein displacement chromatography using poly(diallyl-dimethylammonium chloride) as displacer. Journal of Chromatography, A 2003, 1018, (2), 155-167.
5. Wilkins, J. A.; Xiang, R.; Horvath, C., Selective enrichment of low-abundance peptides in complex mixtures by elution-modified displacement chromatography and their identification by electrospray ionization mass spectrometry. Analytical Chemistry 2002, 74, (16), 3933-3941.
6. Tugcu, N.; Deshmukh, R. R.; Sanghvic, Y. S.; Moored, J. A.; Cramer, S. M., Purification of an oligonucleotide at high column loading by high affinity, low-molecular-mass displacers. Journal of chromatography. A 2001, 923, (1-2), 65-73.
7. Grahek, R.; Milivojevic, D.; Bastarda, A.; Kracun, M., Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Journal of chromatography. A 2001, 918, (2), 319-24.
8. Shukla, A. A.; Deshmukh, R. R.; Moore, J. A.; Cramer, S. M., Purification of oligonucleotides by high affinity, low molecular weight displacers. Biotechnology progress 2000, 16, (6), 1064-70.
9. Ruaan, R. C.; Yang, A.; Hsu, D., Bifunctional adsorbents for hydrophobic displacement chromatography of proteins. Biotechnology progress 2000, 16, (6), 1132-4.
10. Kumar, A.; Galaev, I. Y.; Mattiasson, B., Polymer displacement/shielding in protein chromatography. Journal of chromatography. B, Biomedical sciences and applications 2000, 741, (2), 103-13.
11. Schmidt, B.; Wandrey, C.; Vogt, S.; Freitag, R.; Holzapfel, H., Polycations as displacer in high-performance bioseparation. Journal of chromatography. A 1999, 865, (1-2), 27-34.
12. Ramanan, S.; Velayudhan, A., Displacement chromatography of chemotactic peptides. Journal of Chromatography, A 1999, 830, (1), 91-104.
13. Freitag, R.; Vogt, S., Separation of plasmid DNA from protein and bacterial lipopolysaccharides using displacement chromatography. Cytotechnology 1999, 30, (1-3), 159-167.
14. Vogt, S.; Freitag, R., Displacement Chromatography Using the UNO Continuous Bed Column as a Stationary Phase. Biotechnology Progress 1998, 14, (5), 742-748.
15. Shukla, A. A.; Hopfer, R. L.; Chakravarti, D. N.; Bortell, E.; Cramer, S. M., Purification of an Antigenic Vaccine Protein by Selective Displacement Chromatography. Biotechnology Progress 1998, 14, (1), 92-101.
16. Luellau, E.; von Stockar, U.; Vogt, S.; Freitag, R., Development of a downstream process for the isolation and separation of monoclonal immunoglobulin A monomers, dimers and polymers from cell culture supernatant. Journal of chromatography. A 1998, 796, (1), 165-75.
17. Barnthouse, K. A.; Trompeter, W.; Jones, R.; Inampudi, P.; Rupp, R.; Cramer, S. M., Cation-exchange displacement chromatography for the purification of recombinant protein therapeutics from variants. Journal of Biotechnology 1998, 66, (2,3), 125-136.
18. Vogt, S.; Freitag, R., Comparison of anion-exchange and hydroxyapatite displacement chromatography for the isolation of whey proteins. Journal of Chromatography, A 1997, 760, (1), 125-137.
19. Kundu, A.; Cramer, S. M., Low-molecular-weight displacers for high-resolution protein separations. Analytical biochemistry 1997, 248, (1), 111-6.
20. Velayudhan, A.; Horvath, C., Characterizing, and Compensating for, Enrichment Effects in Displacement Chromatography with Multicomponent Carriers. Industrial & Engineering Chemistry Research 1995, 34, (8), 2789-95.

1. Xia, F.; Nagrath, D.; Garde, S.; Cramer, S. M., Evaluation of selectivity changes in HIC systems using a preferential interaction based analysis. Biotechnology and Bioengineering 2004, 87, (3), 354-363.
2. Sunasara, K. M.; Xia, F.; Gronke, R. S.; Cramer, S. M., Application of hydrophobic interaction displacement chromatography for an industrial protein purification. Biotechnol Bioeng 2003, 82, (3), 330-9.
3. Qi, Y.; Huang, J., Displacement chromatography of isomers and therapeutic compounds. J Chromatogr A 2002, 959, (1-2), 85-93.
4. Shukla, A. A.; Sunasara, K. M.; Rupp, R. G.; Cramer, S. M., Hydrophobic displacement chromatography of proteins. Biotechnol Bioeng 2000, 68, (6), 672-80.
5. Shukla, A. A.; Deshmukh, R. R.; Moore, J. A.; Cramer, S. M., Purification of oligonucleotides by high affinity, low molecular weight displacers. Biotechnol Prog 2000, 16, (6), 1064-70.
6. Ruaan, R. C.; Yang, A.; Hsu, D., Bifunctional adsorbents for hydrophobic displacement chromatography of proteins. Biotechnol Prog 2000, 16, (6), 1132-4.
7. Klimchak, R. J.; Wang, S., The displacement effect of phenylalanine on lysozyme elution in hydrophobic interaction chromatography. Biotechnology Techniques 1997, 11, (7), 497-501.
8. Antia, F. D.; Fellegvari, I.; Horvath, C., Displacement of Proteins in Hydrophobic Interaction Chromatography. Industrial & Engineering Chemistry Research 1995, 34, (8), 2796-804.

1. Sunasara, K. M.; Rupp, R. G.; Cramer, S. M., Purification of Recombinant Brain Derived Neurotrophic Factor Using Reversed Phase Displacement Chromatography. Biotechnology Progress 2001, 17, (5), 897-906.
2. Grahek, R.; Milivojevic, D.; Bastarda, A.; Kracun, M., Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. Journal of chromatography. A 2001, 918, (2), 319-24.
3. Husband, D. L.; Mant, C. T.; Hodges, R. S., Development of simultaneous purification methodology for multiple synthetic peptides by reversed-phase sample displacement chromatography. Journal of Chromatography, A 2000, 893, (1), 81-94.
4. Ramanan, S.; Velayudhan, A., Displacement chromatography of chemotactic peptides. Journal of Chromatography, A 1999, 830, (1), 91-104.
5. Jankowski, J.; Potthoff, W.; Zidek, W.; Schluter, H., Purification of chemically synthesized dinucleoside(5',5') polyphosphates by displacement chromatography. Journal of Chromatography, B: Biomedical Sciences and Applications 1998, 719, (1 + 2), 63-70.
6. Rathore, A. S.; Horvath, C., Displacement chromatography with on-column isomerization. Journal of Chromatography, A 1997, 787, (1 + 2), 1-12.

Trace Component Amplification

SACHEM Published Articles     

1. Haymore, Barry; Little, Charles; Hoffman, Rosemary; Stevenson, Robert; Displacement Chromatography for  Rapid Protein Purification in the Laboratory. American Biotechnology Laboratory. February 2008.
2. Haymore, Barry; Joshi, Hemant; Little, Charles; Hoffman, Rosemary; Stevenson, Robert; Ultrasensitive Impurity Profiles by Displacement Chromatography: A Comparative Study. American Biotechnology Laboratory. October 2007.
3. Little, Charles. Displacement Chromatography Comes of Age. Chromatography Techniques. Sept/Oct 2008.

Other Interesting Articles 

1. Curling, John. HISTORY OF CHROMATOGRAPHY: Process Chromatography: Five Decades of Innovation. BioPharm International. Feb 2, 2007.